專業提供Anti-Phospho-Histone H3 (Ser10)磷酸化組蛋白H3抗體廣泛應用于免疫組化,ELISA,Western Blot IHC-F(免疫組化-冰凍切片),IHC-P (免疫組化-石蠟切片)IP(免疫沉淀), Flow-Cyt等方面。 產品編號 Rs-3186R 英文名稱 Anti-Phospho-Histone H3 (Ser10) 中文名稱 磷酸化組蛋白H3抗體 別 名 H3 histone family member E pseudogene; H3F3; HIST3H3; Histone H3 3 pseudogene. 抗體介紹:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximay 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination are used to mark nucleosomes to create chromatin domains with a range of functions. The information encoded by histone modifications can contribute to the formation and/or maintenance of transcriptionally active and inactive chromatin in response to various signalling pathways. 產品類型 一抗 磷酸化抗體 抗體來源 Rabbit 克隆號 Polyclonal 交叉反應 hu, rat, mo 蛋白分子量 Predicted Molecular Weight: 15KDa 性狀 Lyophilized or Liquid 濃度 1mg/1ml 免疫原 KLH conjugated Synthesised phosphopeptide derived from human Histone H3 around the phosphorylation site of Ser10. 亞型 IgG 產品應用 WB=1:100-500 Elisa=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1/20-1/100 (石蠟切片需做抗原修復)Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. 研究領域 腫瘤 免疫學 染色質和核信號 信號轉導 轉錄調節因子 公司提供的已被國內外廣大科研工作者使用,廣泛用于分子生物學、免疫學等試驗中。