產品詳細信息: 產品編號 Rs-3174R 英文名稱 Anti-Phospho-HDAC3 (Ser424) 中文名稱 磷酸化組蛋白去乙?;?抗體 別 名 RPD3 2; HD 3; HD3; HDAC 3; Histone deacetylase 3 (HD3) (RPD3-2); histone deacetylase 3; RPD 3; RPD3; RPD3-2; SMAP 45; SMAP45. 抗體介紹:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. 產品類型 一抗 磷酸化抗體 抗體來源 Rabbit 克隆號 Polyclonal 交叉反應 hu, rat, mo 蛋白分子量 Predicted Molecular Weight: 50kDa 性狀 Lyophilized or Liquid 濃度 1mg/1ml 免疫原 KLH conjugated Synthesised phosphopeptide derived from human HDAC3 around the phosphorylation site of Ser424. 亞型 IgG 產品應用 WB=1:100-500 Elisa=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1/20-1/100 (石蠟切片需做抗原修復)Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.