產品詳細信息: 產品編號 Rs-1030R 英文名稱 Anti-HMGA1 中文名稱 高遷移率族蛋白A1抗體 抗體介紹:HMGA1 (HMGI/Y; high mobility group AT-hook 1) is a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. There are two splice isoforms of HMGA1 - the full length HMGA1a/HMGI and the shortened form HMGA1b/HMGY. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. HMGA1 is frequently acetylated and is found in the nucleus. Interacts with HIV-1 pre-integration complex. 別 名 high mobility group AT-hook 1; HMG-I/HMG-Y; HMG-R; HMGA 1a; HMGA 1b; HMGA1; HMGI; HMGI/Y; HMGIY; HMGY; MGC12816; MGC4242; MGC4854. 產品類型 一抗 抗體來源 Rabbit 克隆號 Polyclonal 交叉反應 hu, mo, rat, bov, chi 蛋白分子量 Predicted Molecular Weight: 10kDa 性狀 Lyophilized or Liquid 濃度 1mg/1ml 免疫原 KLH conjugated synthetic peptide derived from human HMGA1 C-terminus. 亞型 IgG 產品應用 WB=1:100-500 Elisa=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1/20-1/100 (石蠟切片需做抗原修復)
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
公司提供的)已被國內外廣大科研工作者使用,廣泛用于分子生物學、免疫學等試驗中。
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