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武漢紐斯特生物科技有限公司
武漢紐斯特生物科技有限公司
STK11(P281L)[26158][100µL]CatalogNumber:26158GeneSymbol:STK11
STK11 (P281L) [26158]
[100 µL]
| Catalog Number: 26158 |
| Gene Symbol: STK11, LKB1, PJS, hLKB1 |
| Description: Anti STK11 Mouse Monoclonal Antibody |
| Background: Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer. |
| Immunogen: A synthetic peptide from the internal region of STKwhich includes the mutation of P281L, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:200 |
| Concentration: 0.5mg/ml |
| Host: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ ａnd Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes P281L mutated, but not wild-type STK11 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Download Datasheet: |
| Immunofluorescence: |
| Immunofluorescence of cells expressing STK11 proteins with Anti STK11 (P281L) antibody. HEK293T cells were transfected with pCDNA3-GFP STK11 (WT) plasmid (left column) or pCDNA3-GFP STK11 (P281L) plasmid (right column), then fixed and stained with Anti STK11 (P281L) monoclonal antibody (Cat. #26158). |
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