Description: Anti Orai1 Rabbit Polyclonal Antibody (Orai1-L2)
Background: Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a ~35 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene.
Immunogen: A peptide from the extracellular loop 2 region of human Orai1
Species Reactivity: Orai1-L2 antibody recognizes Orai1 from human.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
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Western blot:
Western blot analysis of Orai1 protein. Human Orai1 plasmid DNA was transiently transfected into HEK-293 cells. Whole-cell lysate was used for western blot in the absence (A) or presence (B) of antigen peptide.