Description: Anti Rab38 Rabbit Polyclonal Antibody
Background: Rab38 is a small GTPase highly expressed in melanocytes. A point mutation in Rab38 has been identified as the genetic lesion responsible for oculocutaneous albinism in chocolate mice. Another point mutation that prevents translation of Rab38 mRNA is the molecular basis of the Ruby gene mutation causing the phenotype of oculocutaneous albinism and prolonged bleeding time in Fawn-Hooded and Tester-Moriyama rats.
Immunogen: A synthetic peptide from the internal region of human Rab38 protein