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Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled, 10µCi

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產品簡介

Cholecystokinin Octapeptide (CCK-8), labeled with 125I. Cholecystokinin is a neuropeptide that exists in several forms, identified by the number of amino acids in the peptide sequence. CCK8 contains 8......

詳細介紹

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligａnd binding assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New Englａnd Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX203:

Kopin, A.S., McBride, E.W., Chen, C., Freidinger, R.M., Chen, D., Zhao, C.M., Beinborn, M. (2003), Identification of a series of CCK-2 receptor nonpeptide agonists: sensitivity to stereochemistry and a receptor point mutation. PNAS, 100 (9): 5525-5530.
Kopin, A.S., Lee, Y.M., McBride, E.W., Miller, L.J., Lu, M., Lin, H.Y., Kolakowski, L.F. Jr, Beinborn, M. (1992), Expression cloning and characterization of the canine parietal cell gastrin receptor. PNAS, 89 (8): 3605-3609.

規格

檢測方法	Radiometric
新鮮的很多天	First Monday of each month
標簽位置	Nominally Labeled
產品品牌名稱	NEN Radiolabeled Ligands
放射性同位素	I-125
放射性核素	¹²⁵I
受體類型	Cholecystokinin
運輸條件	干冰
特殊訂購信息	This is a radioactive product - shipping address must have a license to receive radioactive materials.
治療領域	CNS & Neurologic, Inflammation, Gastrointestinal
產品尺寸	10 µCi