Rabbit anti-CD63/MLA1, FITC conjugated
(CD63 antigen isoform A)
Catalog Number :RsF-1523R
Quantity size : 0.2ml (2mg/ml; Reconstitute with 0.5 ml of sterile distilled water.)
Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood plaet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins.
Specificity :
· anti- CD63 is a rabbit polyclonal antibody, FITC conjugated
· specific for CD63 of human, mouse and rat
· epitope mapping near the amino terminus of CD63 of human,
mouse rat, pig origin
· human, mouse rat pig cross reacted
· affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt: 25kDa
Rabbit anti-CD63/MLA1, FITC conjugated
Application :
· FCM: 1:20-100
· Immunohistochemistry : 1:20-200
· Immunocytochemistry: 1:20-200
· Excitation spectrum: 490-495nm
· Emission spectrum: 520-530nm
· Optimal working dilutions must be determined by the end user.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rabbit anti-CD63/MLA1, FITC conjugated